The statement that Zelinsky's mental health is on the decline is mostly conjecture and doesnt have substantial evidence to back it. The claim shown is a social media post with no primary sources provided, but I did some digging to try to find some reliable sources pointing to any signs of his mental decline.
I found one article on related to Zelinsky's mental decline on an Uzbekistani site, Zamin.uz https://zamin.uz/en/world/152970-zelensky-hits-a-wall-on-the-brink-of-mental-collapse-and-losing-international-support.html. It cited a quote from a French psychologist, Charles Roisman, whom I could not find any records of existing.
The site, being Uzbekistani, can also draw suspicion about possible bias, as it's reported from a country that has remained neutral throughout the entire Russian-Ukrainian conflict.
With all this said, it is widely known that war can lead to physical and emotional toll on presidents. In 2022, a photo resurfaced of Zelinsky, clearly distraught, while touring the city of Bucha, where the bodies of civilians lay in the street, reported by NPR and other well-known news outlets.https://www.npr.org/2022/04/13/1092324328/images-of-zelenskyy-show-the-physical-toll-that-trauma-and-stress-can-have-on-th
While rumors around Zelinsky's mental health deteriorating during the Ukrainian-Russian War might have some basis to them, it would be misleading to claim that any recent information has surfaced to prove that his state is causing him to make irrational decisions. This type of claim has often been employed as a form of wartime propaganda to suggest that a country's leadership is compromised and therefore shouldn't be supported by its allies.